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Company Introduction

3D Medicines, Inc. is a commercial-stage biopharmaceutical company with a mission to help people with cancer live longer and better. Envisioning a future when cancer is managed as a chronic disease, 3D Medicines focuses on the development of differentiated next-generation immuno-oncology drugs, helping cancer patients live with prolonged survival time and a better quality of life. 3D Medicines has established a pipeline with both next-generation biological macromolecule and chemotherapeutic small-molecule drugs, as well as a professional team capable of global development, registration and commercialization operation.

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April 2021

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March 2020
October 2020
November 2020
December 2020
January 2021
March 2021
April 2021

PipelineThe company has established a multi-core collaborative clinical pipeline

Candidate Molecule

Target/
Mechanism

Rights

Preclinical

IND

Phase I

Phase II

Phase Ⅲ

NDA

Partner

Candidate
Molecule

Target/
Mechanism

Rights

Preclinical

IND

Phase I

Phase Ⅱ

Phase Ⅲ

NDA

Partner

  • PD-L1
  • Worldwide
  • MSI-H/dMMR advanced cancer (mono, 2L+, ORR, tissue agnostic indication)

  • BTC (combo with chemo vs. chemo, randomized, OS, 1L)

  • Sarcoma (mono, +ipilimumab, ORR, 2L+)

  • NSCLC (vs standard treatment)

  • NSCLC (combo, 2L+)

  • Urothelial cancer (mono vs. BSC, 1L maintenance, MRCT)

  • G/GEJ advanced cancer (combo with chemo, 1L)

  • TMB-H advanced cancer (2L+ mono)

  • Endometrial cancer (mono, combo with lenvatinib, 2L+)

  • HCC (combo with VEGF inhibitor, 2L+)

  • Renal cell carcinoma (combo with VEGF inhibitor, 1L/ 2L+)

  • Alphamab Group
    Simcere Group
    TRACON
  • WT1
  • Great China
  • Multiple indications

  • AML/MPM/OC/MM

    (Conducted by SELLAS, a licensor of 3D189)

  • SELLAS Group
  • GAS6/AXL
  • Great China
  • NSCLC/OC/RCC/UC

  • OC/RCC/UC

    ( MRCT)

  • OC/RCC/UC

    (Conducted by Aravive, a licensor of 3D229)

  • Aravive
  • COX-2
  • China
  • Post-surgical dental pain/cancer pain

  • Haihe Biopharma Group
  • EP-4
  • China
  • Cancer pain / osteoarthritis

  • Haihe Biopharma Group
  • FGFR1/2/3
  • Worldwide
  • Solid tumors / BTC / UC

  • Haihe Biopharma Group & SIMM
  • TKI prodrug
  • Worldwide
  • HCC / RCC / PC

    IND approved, acceptance notice: CXHL2000597

  • CD47
  • Great China
  • Multiple indications

  • Multiple indications

    (Conducted by ImmuneOncia, a licensor of 3D197)

  • ImmuneOncia
  • CD3+PD-L1
  • Greater China + Worldwide Priority Transfer right
  • Multiple indications

  • Y-Biologics
  • WT1
  • Greater China
  • Multiple indications

  • SELLAS Group
  • Sema4D
  • Worldwide
  • Multiple indications

  • KRAS
  • Worldwide
  • Multiple indications

Pipeline

  1. Envafolimab
  2. 3D189
  3. 3D229
  4. 3D1001
  5. 3D1002
  6. 3D185
  7. 3D011
  8. 3D197
  9. 3D057
  10. 3D059
  11. 3D060
  12. 3D062

CEO MESSAGE

"With the increasing incidence of cancer, cancer has become one of the major public health problems facing mankind; it not only poses a major threat to human health, but also causes a serious burden to economic and social development.

With commitment to the R&D and commercialization of a next-generation of innovative immuno-oncology drugs, 3D Medicines hopes to provide cancer patients across the globe with more effective, more accessible, and more convenient options of next-generation immuno-oncology drugs, thus helping them to live longer and better."


-- John Gong, M.D., Ph.D., Chairman and CEO of 3D Medicines Inc.

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